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Chromogranin A-phosphatidic acid association coordinates late stages of regulated exocytosis


Genetic screening identifies WNT5A/RYK as a determinant of extracellular vesicle fate


Caveolae mechanics in cellular functions and disease


Diffusing caveolin-1 scaffolds regulate mechanosignalling


High‐Content Immunofluorescence Quantification of Transcription Factors: Application to pSMADs for BMP/TGFβ Signaling Pathways


Membrane lipid poly-unsaturation selectively affects dopamine D2 receptor endocytosis


α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron–microglia communication


icone personne Chakraborty, et al. 2026

icone laboratoire Pasteur Institute

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Clathrin-independent endocytosis and retrograde transport in cancer cells tune immune synapse organization and CD8 T cell response


Human iPSC-derived airway models enable comparative analysis of SARS-CoV-2 infection in healthy and COPD bronchial epithelium


Biology and therapeutic potential of extracellular vesicle targeting and uptake


Keratin intermediate filaments mechanically position melanin pigments for genome photoprotection


Cryo-correlative light and electron tomography of dopaminergic axonal varicosities reveals non-synaptic modulation of cortico-striatal synapses


Spatiotemporal coupling of caveolae mechanosensing and RhoA-GEFs regulates cell polarity and directional migration


Functional and Morphological Plasticity of the Endolysosomal System: Pigment Organelles at the Crossroads of Physiology and Pathology


Mechanosensitive interactions of tumoroids with an engineered environment promote cell proliferation and enhance drug response detection.


Influenza A virus induces PI4P production at the endoplasmic reticulum in an ATG16L1-dependent manner to promote the egress of viral ribonucleoproteins


Designing New Natural‐Mimetic Phosphatidic Acid: A Versatile and Innovative Synthetic Strategy for Glycerophospholipid Research


Lipid asymmetry and membrane trafficking: Transbilayer distribution of structural phospholipids as regulators of exocytosis and endocytosis


HIV-1 assembly – when virology meets biophysics


Phospholipid Scramblase 1 Controls Efficient Neurotransmission and Synaptic Vesicle Retrieval at Cerebellar Synapses


Restoring cellular copper homeostasis in Alzheimer disease: a novel peptide shuttle is internalized by an ATP-dependent endocytosis pathway involving Rab5- and Rab14-endosomes


HIV-1 diverts actin debranching mechanisms for particle assembly and release in CD4 T lymphocytes


F-actin nanostructures rearrangements and regulation are essential for SARS-CoV2 particle production in host pulmonary cells


Advanced Imaging Approaches to Reveal Molecular Mechanisms Governing Neuroendocrine Secretion


Chromogranin A preferential interaction with Golgi phosphatidic acid induces membrane deformation and contributes to secretory granule biogenesis


Myosin 1b and F-actin are involved in the control of secretory granule biogenesis