CLUB EXOENDO

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Membrane Domains and Virus Assembly (MDVA)

IRIM (ex-CPBS)
34090 Montpellier, France
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Members

Delphine Muriaux - delphine.muriaux@irim.cnrs.fr
Cyril Favard - cyril.favard@irim.cnrs.fr
Claire Lacouture - claire.lacouture@irim.cnrs.fr

Keywords

RNA enveloped viruses, virus assembly, RNA and protein-lipid interactions, VLP, exosomes, actin cytoskeleton, fluorescence microscopies

Description

Our team is interested in the role of viral and cellular proteins and their interactions with viral RNA and host cell lipids during viral translation and virus assembly.

We study these phenomena quantitatively and at the single molecule level, on biomimetic membrane model systems, in host cells and in living multicellular organisms.

Biological models

biomimetic membranes, host cell lines, primary lymphocytes, Air Liquid Interface lung models

Scientific Publications

HIV-1 assembly – when virology meets biophysics


Lacouture, et al. 2024

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HIV-1 diverts actin debranching mechanisms for particle assembly and release in CD4 T lymphocytes


Dibsy, et al. 2023

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F-actin nanostructures rearrangements and regulation are essential for SARS-CoV2 particle production in host pulmonary cells


Swain, et al. 2023

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