Diffusing caveolin-1 scaffolds regulate mechanosignalling
Mani, et al. 2026
View the publicationInstitut Curie, U1339 Inserm UMR3666 CNRS Chemical Biology of Cancer
Team
Membrane Mechanics and Dynamics of Intracellular Signaling
Members
Christophe LAMAZE (DRCE Inserm), Cedric BLOUIN (CRCN Inserm), Christine VIARIS DE LESEGNO (IR Inserm), Céline GRACIA (IE CNRS), Victor BRETON (Postdoc), Subhamoy JANA (Postdoc), Cristian SACQUEL (Postdoc), Nerea MARTOS GUILLAMI (PhD), Bastien GUYOT (PhD), Pamela TRONCOSO GONZALEZ (IE).
Keywords
caveolae, lipid, membrane receptor, mechanobiology, signaling
Description
The projects developed by the “Membrane Mechanics and Dynamics of Intracellular Signaling” team are based on new concepts and original analyses developed by the team over the last ten years for the study of the cellular biology of membrane trafficking, plasma membrane dynamics and mechanics, and their roles in intracellular signaling.
Biological models
Cell models: triple negative breast cancers, glioblastoma, colon cancer and associated fibroblasts
Scientific Publications
Spatiotemporal coupling of caveolae mechanosensing and RhoA-GEFs regulates cell polarity and directional migration
Singh, et al. 2025
View the publication